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The Tat-SIRT5-CTM peptide specifically blocked the interaction of SIRT5 with ANXA1, led to SIRT5 degradation and thereby inhibiting SIRT5-mediated desuccinylation of ANXA1, which in turn ...

On the left are the representative images of TTC-stained tissues from mice treated with the Tat-SIRT5-CTM peptide. In the center is the mNSS results showing the extent of neurological deficits at ...