Rhodanese, an endogenous enzyme, then facilitates the formation of thiocyanate, a much less toxic metabolite, which is renally excreted. The creation of methemoglobinemia through the use of ...

Figure 3: Interaction of apical domain proteins with unfolded rhodanese and DHFR. We conclude from these data that the apical GroEL domain in isolation has largely lost the chaperone activity ...