In the case of the trp operon, the ligand tryptophan is required for the repressor to work (repressible negative regulation). But other operons respond to the presence of their small molecule ...

Bacteria, which are susceptible to infection by bacteriophages, often carry multiple genes encoding anti-phage defense ...

Molecules can interfere with RNA polymerase binding. An inactive repressor protein (blue) can become activated by another molecule (red circle). This active repressor can bind to a region near the ...

Arvinas to present preclinical data for PROTAC BCL6 degrader & ARV-393 at 2025 AACR annual meeting in Chicago: New Haven, Connecticut Wednesday, April 23, 2025, 18:00 Hrs [IST] Ar ...

The U.S. Immigration and Customs Enforcement (ICE) revealed on Monday the capture of a Cuban national who allegedly concealed ...

ARV-393 is Arvinas' investigational PROteolysis TArgeting Chimera (PROTAC) degrader targeting the B-cell lymphoma 6 protein ...