Amgen's cholesterol-lowering antibody Repatha is being launched in Europe at well below the new drug's cost in the US, raising the chance that American payers will seek hefty discounts on the drug.

Leqvio (inclisiran) and Repatha (evelocumab) are prescription injectable medications used to treat high cholesterol. They specifically target low-density lipoprotein cholesterol (LDL-C), or "bad ...

The results give a clear advantage to Sanofi and Regeneron in the duel with Repatha, which like Praluent, is a PCSK9 inhibitor drug. While Amgen has data showing Repatha can reduce heart attacks ...

It’s not known whether Repatha (evolocumab) is safe to use while pregnant or breastfeeding. Certain factors may determine whether you should use the drug during this time. It’s not known ...

Key growth drivers included Repatha and EVENITY, which collectively grew 35% year-over-year, contributing nearly $1 billion in sales growth. Repatha achieved $2.2 billion in sales, with U.S ...

[Repatha package insert;9a] When PCSK9 is inactivated or inhibited, the LDL receptor/LDL cholesterol (LDL-C) particle complex is still internalized by endocytosis; however, once in the cell ...