Roche will invest $50 billion in U.S. manufacturing, including a new plant in Indiana. The Trump administration is considering tariffs on drugmakers.

The pharma giant said the investment would create more than 12,000 jobs, as it joins rival Novartis in expanding its footprint in the country amid President Trump’s tariff threats.

With threats of tariffs hanging over the pharmaceutical industry, Switzerland’s Roche announced on Tuesday that it will invest $50 billion in the United States over the next five years, expanding its existing facilities and building new manufacturing plants and research centers.