has certain genetic predispositions that increase the risk of developing the disease. “A few such conditions like Li-Fraumeni syndrome, Down syndrome, and mutations in genes like TP53, RUNX1 ...

A new review published in Genes & Diseases highlights the transformative ... targeting key proteins like Smad3, PDGFR-β, Runx1, and PPAR-γ, which are central to fibrosis development.