Researchers have developed a machine learning model that predicts Cas9 proteins that can be tailored with designer properties for therapeutic use.

The integration of RNAi with other technologies, such as CRISPR-Cas9 gene editing and high-throughput screening, will accelerate the discovery and development of new RNAi-based therapies for a wide ...

CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the ...

What are NGTs, how do they differ from GMOs and how are they agriculturally applied and regulated in the EU? View on euronews ...

To find more distantly related proteins, they used an iterative process: from Cas9, they identified a protein called IS110, ...

One of the barriers to using CRISPR-Cas9 gene editing in the clinic is the possibility ... throughout the genome and show in mice that a carefully designed guide RNA strand does not produce any ...

The Cas9 protein is the most widely used by scientists. This protein can easily be programmed to find and bind to almost any desired target sequence, simply by giving it a piece of RNA to guide it ...

Scientists realized that they could edit and disrupt gene function in eukaryotes by engineering customizable short guide RNA to direct the enzymes to introduce cuts at specific points in the genome.