The natural RNAi mechanism can be directed by either short interfering RNA (siRNA) or microRNA (miRNA ... activity means that miRNA can act on many different mRNAs, potentially silencing hundreds of ...

The discovery of RNAi dates back to the 1990s when researchers observed unexpected gene silencing in plants and fungi. In 1998, Andrew Fire and Craig Mello published a groundbreaking study ...

What do cells, genes, mutations, transposons, RNA silencing, and DNA recombination have in common? All were discovered first in plants. It sounds grandiose, but it’s true, and plant biologists delight ...

Fungal infections are on the rise globally. According to a study by the Manchester Fungal Infection Group, in 2022, ...

It is also looking to expand its RNA silencing research, potentially bringing it into competition with biotech heavyweights such as Alnylam, something that Mortazavi focused on during his long ...

Though recent discoveries have revealed how rice plants mitigate such threats by initiating immune responses against ...

Adverse genetic mutations can cause harm and are due to various circumstances. “Jumping genes” are one cause of mutations, ...

Adverse genetic mutations can cause harm and are due to various circumstances. "Jumping genes" are one cause of mutations, but cells try and combat them with a specialized RNA called piRNA.

However, siRNAs have not been applied to regulate bacterial genes due to the lack of RNAi regulatory machinery, i.e., RNA-induced silencing complexes (RISCs), in bacteria. In addition, efficient ...