RPA has a higher affinity for ssDNA than Rad51, and it therefore can inhibit recombination by blocking Rad51's access to the single strand needed for invasion. In yeast, however, binding of Rad51 ...

The mechanism of homologous recombination: Our long-term research objective is to study the mechanisms of homologous recombination in eukaryotic systems. Genetic recombination is the molecular process ...