In yeast, for instance, the helicase Srs2 dismantles the Rad51-ssDNA complex, while the proteins Sgs1 and BLM inhibit the complex. It is thought that these proteins play a role in preventing ...

Multiple RAD51 proteins bind along the length of broken ... It also revealed that HELQ has another role: it can zip up two aligning strands of DNA to form the double helix. HELQ tethers to ...

The BRCA2 gene is known to play a crucial role in repairing and stabilizing ... NYU—discovered a dynamic interplay between the BRCA2, RAD51 (a protein that helps repair damaged DNA), and PARP1 ...

Homologous recombination plays essential roles in the repair of DNA double strand breaks ... This reaction is carried out by the RecA/Rad51 family of ATPases. In repair, the DSB is resected to produce ...