the PARP1 proteins can destabilize repair complexes and hinder DNA repair processes initiated by RAD51. Remarkably, Jensen said, the BRCA2 gene effectively shields these complexes, maintaining the ...

RPA has a higher affinity for ssDNA than Rad51, and it therefore can inhibit recombination by blocking Rad51's access to the single strand needed for invasion. In yeast, however, binding of Rad51 ...

Multiple RAD51 proteins bind along the length of broken ... used this method to understand how the accuracy of CRISPR/Cas9 gene editing changes as DNA is distorted under strain 2.