When urine bubbles increase and murky symptoms appear, it is easy to regard it as a simple condition deterioration. However, ...

BOSTON -- Patients with focal segmental glomerulosclerosis (FSGS) achieved some degree of proteinuria remission more often and more quickly on sparsentan (Filspari) than irbesartan (Avapro ...

The drug is a once-daily nonsteroidal pill that can be taken along with standard supportive care to reduce protein in the urine, known as proteinuria. IgAN, which is also called Berger’s disease ...

IgA nephropathy (IgAN) is an autoimmune disorder that affects the kidneys by impairing the filtration function of the small ...

Aprocitentan, on top of background therapy, showed clinically meaningful and durable blood pressure (BP) reduction and a decrease in proteinuria ...

The FDA granted accelerated approval to atrasentan (Vanrafia) for the reduction of proteinuria in adults with primary immunoglobulin A (IgA) nephropathy, maker Novartis announced late on Wednesday.

Atrasentan is approved for proteinuria reduction in primary IgA nephropathy, a condition risking kidney failure. The phase 3 ALIGN study showed atrasentan reduced proteinuria by 36.1% compared to ...

Following a meeting with the US FDA, clinical-stage biotech Dimerix has confirmed the appropriate primary endpoint for full ...