It is the original example of a group of diseases, known as the "transmissible spongiform encephalopathies" (TSE), sometimes known as the "prion" diseases. The diseases include Creutzfeldt Jakob ...

A system for the rapid amplification of misfolded prion oligomers provides new evidence supporting the prion hypothesis and may offer a powerful diagnostic tool. The prion hypothesis remains ...

These observations suggest that a diagnostic test for prion infections based on CSF or other non-brain tissues or excretia may be possible. Further studies will be required to demonstrate the ...