A surface protease helps Yersinia pestis plow its way through the body during pneumonic plague. During the 14th through 16th centuries, Y. pestis caused a pandemic of plague that killed a third of ...

Over 80% of plague cases in the U.S. have been the bubonic form, according to the CDC, though the pneumonic form is more ...

Septicemic plague infects the bloodstream. Pneumonic plague, which can be passed from human to human, occurs when the bacillus moves into the pulmonary system, choking off breathing. Infection in ...

Untreated bubonic plague can progress to septicemic or pneumonic plague. Septicemic plague—which can also result from flea bites or handling an infected animal—is characterized by symptoms ...

Bubonic plague produced painful swellings - buboes. This form was mainly spread by fleas carried by rats. Pneumonic plague attacked the victim’s lungs and was spread by personal contact.

We currently lack a safe, effective and licensed vaccine for pneumonic plague, which is nearly always fatal and has been weaponized. Yersinia pestis overcomes host defense, in a large part ...

Two patients from Inner Mongolia were quarantined in Beijing suffering from pneumonic plague, authorities said last week. A 55-year old man from the same region was later diagnosed with bubonic ...

As noted above, the licensing of pneumonic plague vaccines will rely on efficacy data from animal studies and safety data from human trials. In addition, licensure will require assays that bridge ...