Right timing of cell division His group has now discovered that Plk1 is not essential for the start of cell division. "Rather, it acts as a molecular switch to ensure that cells start dividing at ...

Erroneous or uncontrolled cell division can have serious consequences, leading to diseases such as cancer. Plk1 plays a key role in this regulatory process. It activates other proteins involved in ...

More information: Monica Gobran et al, PLK1 inhibition delays mitotic entry revealing changes to the phosphoproteome of mammalian cells early in division, The EMBO Journal (2025). DOI: 10.1038 ...