Findings suggest that elevated plasma levels of ADM impair insulin receptor function in endothelial cells, leading to reduced vascular insulin delivery and systemic insulin resistance. Obesity is ...

Plasma 17-hydroxycorticosteroid levels were measured after insulin-induced hypoglycemia in a group of 10 adults receiving alternate-day steroid therapy. In these patients, who had either ...

After 12 h of overnight fasting following 3 d of standardized diet at the Obesity Metabolism unit 2, we measured plasma insulin in unstressed conditions (intravenous microcatheter placed in a ...

Plasma glucose was measured by enzymatic hexokinase photometric assay (Konelab Systems reagents; Thermo Fischer Scientific, Vantaa, Finland). Insulin was determined by immunoassay (ADVIA Centaur ...

Second, we found that metabolic concentrations of plasma LPS are a sufficient molecular ... Finally, the LPS receptor CD14, by controlling insulin sensitivity, sets the threshold at which ...