1). The four DNA fragments (A, B, C and D) encompassing the full–length HIV–1 genome were first amplified individually in a high–fidelity PCR by using Pfu DNA polymerase (Stratagene).

He added: "While our lead DNA pol IIIC inhibitor is Phase 3-ready for oral treatment of C. difficile Infection, our second generation compounds in our program are systemically absorbed for ...