One such avenue is through the protein tyrosine phosphatase non-receptor type 2 (PTPN2) and its close superfamily member, PTPN1, identified in previous research as crucial modulators involved in ...
The clinical-stage projects include two immuno-oncology candidates in phase 1 testing – both PTPN2 inhibitors – that "act at multiple steps in the cancer immunity cycle", and a drug for a ...