Further investigation into PP2A-mediated signaling pathways in T cell biology This research provides novel insights into the molecular regulation of CD8+ T cell function and establishes PP2A as a ...

SpringWorks is working to add another candidate to its clinical pipeline, with a filing to study the PP2A activator SW-3431 in humans planned for this year.

Protein phosphatase 2a (PP2A) has an important role ... Moreover, in CML, deficiencies in most of the major repair pathways have been found, including BER, NER, NHEJ and HR.

The roles of PP1, PP2A and PP2Cγ and PP2Cδ in pre-mRNA maturation ... complexes that are involved in a diversity of signalling pathways. The identification and characterization of phosphatase ...