But they didn’t know why. Now, two UC San Francisco research teams and a team from the University of Queensland (Australia) have identified platelet factor 4 (PF4) – a small protein released by blood ...

Studies of three different techniques for combating the cognitive decline that accompanies aging found that they all increase levels of a protein called platelet factor four, or PF4, in mice.

Vaccine-induced immune thrombocytopenia and thrombosis (VITT) is associated with antibodies that target platelet factor 4 (PF4) and are heparin-independent. VITT antibodies are implicated in acute ...

This week, a team led by Saul Villeda at the University of San Francisco discovered a surprising candidate: platelet factor 4 (PF4). The protein’s not a stranger to science or life—your body likely ...

Now, two studies identify platelet factor 4 (PF4) as the key mediator of this killing mechanism. But how does PF4 actually kill the parasite? HDPs are known to act by disrupting the target cell ...

Studies suggest that some inoculated people develop an immune response that attacks a protein called platelet factor 4 or PF4, which makes platelets form clots. Those platelets get used up before ...

Heparin-induced thrombocytopenia is a prothrombotic disorder mediated by IgG antibodies that bind to conformational epitopes on PF4 when it is complexed with heparin. Typically, the platelet ...

Previous studies have shown that patients with VITT produce antibodies that stick to a protein called Platelet factor 4 (PF4) to create a large cluster of molecules called an immune complex.

The protein is called platelet factor 4 (PF4). We know that in the course of infection, many people make antibodies that stick to PF4 as part of the immune response, but these antibodies usually ...

"This adenovirus-associated disorder is now one of four recognized anti-PF4 disorders," said Moll, professor of medicine in the Department of Medicine's Division of Hematology. "We hope that our ...