Platelet-Derived Growth Factor Receptor Alpha (PDGFRA) plays a role at multiple levels in the development of high-grade gliomas and represents a promising therapeutic target. Previous attempts to ...

Platelet-Derived Growth Factor Receptor Alpha (PDGFRA) plays a role at multiple levels in the development of high-grade gliomas and represents a promising therapeutic target. Previous attempts to ...

We were excited to see that avapritinib essentially shut off PDGFRA signaling in mouse brain tumors." Carl Koschmann, M.D., ChadTough Defeat DIPG Research Professor and clinical scientific ...

More information: Soniya Bastola et al, Endothelial-secreted Endocan activates PDGFRA and regulates vascularity and spatial ...

Avapritnib has been approved to treat advanced systemic mastocytosis and indolent systemic mastocytosis and gastrointestinal stromal tumors with a platelet-derived growth factor receptor alpha (PDGFRA ...

ZOLAR is a first-in-human, proof-of-concept and biodistribution trial that uses positron emission tomography (PET) to evaluate olaratumab, a monoclonal antibody, as a therapeutic radiopharmaceutical ...