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Australian researchers have discovered that a single mutation in the DNA sequence for a methylation enzyme dysregulates key ...
Scientists at the University of Michigan Rogel Cancer Center have found a promising new way to fight one of the most ...
Sustained reactivation of mutant p53 drives durable anti-tumor activity across models, including KRAS co-mutant tumorsFMC-220 selectively stabilizes p53 Y220C at lower doses, overcoming key ...
In the study, patients with advanced solid tumors must be HLA-A*02:01 positive and harbor a p53 R175H mutation.
May Overcome Resistance to Azacitidine-Venetoclax Regimen and Trigger Apoptosis of TP53 Mutated AML CellsNEW YORK, April 28, 2025 (GLOBE NEWSWIRE) -- SELLAS Life Sciences Group, Inc. (NASDAQ: SLS) ...