EurekAlert!12d
Beyond the cure: Navigating hepatocellular risk and surveillance after hepatitis C eradication in the direct-acting antiviral era
Direct-acting antivirals (DAAs) have dramatically changed the landscape of chronic hepatitis C virus (HCV) treatment and ...
News Medical on MSN10d
Review explores the underlying mechanisms of hepatocarcinogenesis post-HCV eradication
Hepatitis C virus (HCV) infection remains a major global health burden, affecting millions worldwide and contributing significantly to hepatocellular carcinoma (HCC) development.
Nature1mon
Exploiting the PI3K/AKT Pathway for Cancer Drug Discovery
In contrast to p53 and other tumour-suppressor pathways ... the recent demonstration of the intricate role of mTOR in regulation of PI3K/AKT demonstrates that a detailed understanding of the ...
EurekAlert!7d
Why some breast cancer treatments stop working
This figure illustrates the major signaling pathways and their intricate crosstalk in BC, focusing on the GPCR, RTKs, RAS/RAF/MEK1/2/ERK1/2, MAPK, HER2, PI3K/Akt/mTOR, Wnt/β-catenin, NF-κB ...
Hosted on MSN2mon
Desert plant shows promise as colorectal cancer treatment
“Additionally, it blocked the PI3K/AKT/mTOR pathway, which plays a major role ... profiles including some with and without the crucial p53 tumor suppressor gene. This comprehensive approach ...