The 92-year-old bacterial geneticist who helped pioneer the study of gene regulation has passed away. Scientists dive into the genomes of whales, elephants, and other animal giants looking for new ...

The operon is regulated by Lac repressor, the product of the lacI gene, which is transcribed from its own promoter (PI). The repressor inhibits transcription by binding to the lac operator (O).

Can the presence of glucose itself activate the genes that will break it down? It does in bacteria through a process known as positive transcription control.

Microbial genes, including cntA/B, the cai operon, and the gbu gene cluster, have been implicated in converting L-carnitine into TMA(O). However, the key genes and microbes remain underexplored.