MECP2 mutations are the major genetic mutation associated with Rett syndrome. Diagnosis is made via observable features, which include regression of developmental features, including language and ...

Alteration in the expression of methyl-CpG-binding protein 2 (MeCP2) has been linked to a number of neurological disorders, including Rett syndrome (RTT). A recent modifier screen in flies has ...

This suggested to us that the nuclear inclusions are probably protective by sequestering ... is caused by mutations in the gene encoding methyl-CpG-binding protein 2 (MECP2). Located on the X ...