In contrast to neural crest-derived stem cells, which have a limited self-renewal capacity, pNSCs closely resemble brain-derived NSCs and show the ability to sustain neurogenesis over an extended ...

Intro text here... Abnormal neural crest cell development is associated with numerous pathologies including craniofacial malformations such as cleft lip and cleft palate, rare syndromes, and ...

To answer this question, Dr. Barriga and his team identified an enzyme known as voltage-sensitive phosphatase 1 (Vsp1) found in neural crest cells. Due to the versatile structure of Vsp1, it ...

The image shows induced human neural crest cells. Human embryonic stem cells display neural crest characteristic expression after only five days of culture under WNT induction. Transcription ...

The skull and facial bones arise from what are known as neural crest cells, which are produced on the back of the embryo and are developmentally closest to the cells of the central nervous system.

Specific functional, electric firing properties of those neurons are shown by electrophysiology. Directing neural crest and sensory placode lineages Multipotent neural crest (NC) precursor cells have ...

Another key regulator is SOX10, which is required for the gereration of Schwann cell precursors from the neural crest. Understanding the signals that regulate the appearance of glial ...

Peripheral NSCs (pNSCs) are composed of SOX1 + cells that originate from neuroepithelial cells and not neural crest cells, share features with brain NSCs and contribute to peripheral neurogenesis ...