Scientists have tapped into the Summit supercomputer to study an elaborate molecular pathway called nucleotide excision ...

The Summit supercomputer revealed how damaged strands of DNA are surgically repaired by a molecular pathway called nucleotide excision repair, or NER. NER’s protein components can change shape ...

This method is often referred to as "light repair," because it is dependent on the presence of light energy. (In comparison, NER and most other repair mechanisms are frequently referred to as ...

Five of the conditions (xeroderma pigmentosum, Cockayne's syndrome, trichothiodystrophy, Down syndrome, and triple-A syndrome) display a defect in the nucleotide excision repair pathway ...

The native structure of genomic DNA can be damaged in many ways, both by external agents and from within the cell as a consequence of normal metabolism In an effort to maintain their genomic ...