Now, researchers have harnessed the power of a resident drug courier, i.e., microglia. Researchers genetically engineered human iPSC-microglia to deliver neprilysin when the cells are near amyloid ...

In the new study, the researchers examined dopamine's role in the production of an enzyme known as neprilysin. It can break down beta-amyloid proteins before they can form plaques. However ...

The dual-action agent LCZ696 blocks the angiotensin II receptor (via a valsartan moiety) and inhibits neprilysin (via an AHU377 moiety). In a phase II trial, this drug “demonstrated superior ...

The blood-brain barrier border protects the brain by regulating the flow of molecules, peptides, and cells, but it also keeps out many therapeutics. Now, researchers have harnessed the power of a ...