Nanoparticles of a certain size range, with minor macrophage uptake and prolonged blood half-life time can passively accumulate on tumors, taking advantage of the progressive permeation through ...

Researchers also engineered a specific type of immune cell—macrophages—to carry the nanoparticles to the tumor site. Macrophages are naturally attracted to tumors, and when loaded with ...

Effect of nanoparticle shape on biodistribution & macrophage uptake The rate of internalization of a nonspherical nanoparticle depends on its angular orientation relative to the cell membrane.

Using lipid nanoparticles (LNPs) loaded with RNA encoding IL-4, a cell-to-cell signaling protein known as a cytokine, the therapy targeted dysfunctional macrophages while simultaneously reducing ...

Macrophages recognize, engulf, and clear out foreign invaders, whether they’re microbes entering through a wound or a drug-loaded nanoparticle injected to target disease. Previously, researchers have ...

which could be beneficial in cancer therapy by targeting tumor-associated macrophages[5]. Overall, the research indicates a growing interest in the green synthesis of selenium nanoparticles and ...

This supports previous research showing size-dependent differences in how nanoparticles interact with cells and ... are more readily phagocytosed by macrophages compared to microplastics, which ...