Fig. 1 | The NLRP3 inflammasome is an upstream activator of IL-1β and IL-18. NodThera is employing novel chemistry to create small molecules that inhibit the NLRP3 inflammasome that have now ...

Figure 1: Activation of the NLRP3 inflammasome by aluminium salts ... which induce the release of lysosomal host proteases, and/or to some as-yet-unknown mechanisms that work synergistically ...

Fats and other cellular materials reach the lysosome through three main pathways: endocytosis, phagocytosis, and autophagy. In endocytosis, the cell takes in materials from outside by wrapping ...