A mutated gene results in the loss of neurofibromin, which allows cells to grow uncontrollably. Neurofibromatosis Type 2 The NF2 gene is located on chromosome 22, and produces a protein called ...

This gene encodes a protein known as merlin. Mutations in the NF2 gene disrupt the function of merlin, which is part of a complex molecular signaling pathway that regulates how cells grow and divide.

An international leader in advancing neurofibromatosis research, UAB serves as the national coordinating center for the NF Clinical Trials Consortium. This collaborative group of 15 primary and 10 ...