Neurofibromatosis is a group of rare genetic disorders that cause benign tumors to form on nerve tissue. Tumors in this disorder are usually noncancerous (benign), but can sometimes become ...

Neurofibromatosis type 2 is caused by a change in the NF2 gene located on chromosome 22. This gene encodes a protein known as merlin. Mutations in the NF2 gene disrupt the function of merlin, which is ...

An international leader in advancing neurofibromatosis research, UAB serves as the national coordinating center for the NF Clinical Trials Consortium. This collaborative group of 15 primary and 10 ...

This included three cultures from non-tumor nerve of subjects with NF1, leading to matched heterozygous SC lines for two of the subjects whose NF1-null Schwann cells also immortalized (ipNF95.11b ...