Instead of the enzyme mechanism described in biochemistry text-books ... Of particular note is the proposal that ‘entropic guidance’ contributes to catalysis of NADH hydride transfer by dehydrogenases ...
NQO1 binds many IDPs, including p53, p73α and monomer ODC, and protects them from 20S proteasomal degradation by a mechanism requiring NADH 11. While NQO1, a 20S proteasome gatekeeper ...
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