The first generation of mAbs, unveiled in 1975 (ref. 1), were murine mAbs derived from mouse B-cell hybridomas (see “Monoclonal antibodies by design”). However, as murine mAbs moved into ...

EGFR: EGF receptor; mAb: Monoclonal antibody; VEGFR: VEGF receptor. The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in ...

examined the efficacy of two novel anti-osteopontin monoclonal antibodies (mAbs; 23C3 and F8E11) in the treatment of murine collagen-induced arthritis (CIA), an animal model of human RA.

High throughput production of chimeric antibodies with murine-constant regions and human-variable regions ... Inc., to discover the progress towards humanized monoclonal antibodies with transgenic ...