TCR-peptide–MHC (pMHC) class I complexes for which crystal structures have been determined (mouse 2, 2C–dEV8–H-2K b, human 3,4: A6–Tax–HLA-A2 and B7–Tax–HLA-A2) indicate a common ...

6,7 (5) The T cell receptor (TCR) is a protein complex that recognizes different peptides and triggers T cell activation. A TCR genetically engineered to bind specific peptide-HLA complexes can ...