A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse. Nature Genet. 25 , 440–443 (2000). CAS PubMed Google Scholar ...

To determine whether the obese phenotype of cloned mice is transmitted genetically through the germline, we mated male B6C3F1 clones derived from fibroblast cell nuclei with female B6C3F1 clones ...

Advanced imaging technologies are uncovering surprising roles for CD8+ T cells—not just in immune defense, but also in supporting tissue repair and regeneration.

The Mouse Behavioral Phenotyping Core (MBPC) performs behavioral testing on murine disease models to assay motor, learning, emotional and social phenotypes that may be present. We offer a wide variety ...

The newer Mouse Strain Phenotype Database also consists of 3-D anatomical constructs of MRI images, but it showcases both male and female mice of a variety of strains.

Understanding the relationship between a genotype and phenotype can be extremely useful in a variety of research areas. A particularly interesting area is pharmacogenomics.Genetic variations can occur ...

The University of California, Davis, has been awarded just over $12 million from the National Institutes of Health under the third and final five-year phase of the Knockout Mouse Phenotyping Project, ...

Two major studies by international teams published today (June 26) show the value and potential of genetically modified mice in biomedical research — and also the pitfalls of conducting research with ...

The Mouse Metabolism and Phenotyping Core is a comprehensive fee-for-service rodent phenotyping core providing investigators with a wide variety of state of the art equipment and techniques. We work ...

September 15, 2007 (Vol. 27, No. 16) Without Proper Training and Organization, Research Dollars Will Be Wasted The biotechnology industry faces a major problem; too many genetically modified mice ...

Employing a new, standardized phenotyping pipeline and mouse strains of a single specific genetic background called C57BL/6N, the researchers established both the time of embryo death and the ...

The mouse phenotype is nicknamed "Supermodel." "This mouse is important because it has revealed a new regulatory protein that's very important for normal metabolism, ...