Impact of CD2AP deficiency in microglia in Alzheimer’s disease (AD). Microglial CD2AP levels are increased in AD, leading to elevated CSF1R signaling and C1q expression and cytoskeleton ...

Phase 2 ARCHER Data Support Therapeutic Potential for ANX007 to Preserve Vision in Patients who have Dry Age-related Macular Degeneration (AMD) with Geographic Atrophy (GA) Phase 3 ARCHER II Trial ...

Their study sheds new light on the possibility of effectively replacing defective microglia—the brain's immune cells—marking a potential breakthrough in the treatment of neurodegenerative ...

Now, researchers have harnessed the power of a resident drug courier, i.e., microglia. Researchers genetically engineered human iPSC-microglia to deliver neprilysin when the cells are near amyloid ...

A study led by Turkish researcher Pinar Ayata unveiled a critical mechanism involving microglia—specialized immune cells in ...

While investigating if microglia, the resident immune cells of the brain, and neurons communicate through TNTs, Zurzolo and her team uncovered a protective role for microglia in neurodegenerative ...

This process is considered as a basis for long-lasting memory. In this study, we will elucidate roles of C1q family proteins in regulation of synapse formation and maintenance in adult brain.

Microglia are a type of small macrophage-like glial cell in the central nervous system. Microglia can engage in phagocytosis, and are involved in immune responses within, as well as the ...

LI Hanjie from the Shenzhen Institutes of Advanced Technology (SIAT) of the Chinese Academy of Sciences has revealed the presence of microglia in the peripheral nervous system (PNS) and identified ...