Iron-dependent ferroptosis, a non-apoptotic cell death mechanism, is gaining attention for its role in immune suppression. Ferroptosis, driven by excessive lipid peroxides and iron-dependent ...

Ferroptosis has garnered strong interest due to its therapeutic potential in addressing therapy-resistant and metastasizing cancers, and its involvement in neurodegenerative diseases.

Patrizia Agostinis (VIB-KU Leuven) has found that melanoma cell populations protect themselves from a form of cell death called ferroptosis by secreting the lipoprotein apolipoprotein E (ApoE).