By isolating the key DNA sequence from the virus and implanting it in embryos (along with, in varying combinations, the cancer-promoting oncogenes myc and ras), they created a mouse susceptible to ...

More information: Andrew Kent et al, A stromal inflammasome Ras safeguard against Myc-driven lymphomagenesis, Nature ...

They transformed E13.5 mouse embryonic fibroblasts (MEFs), which do not express telomerase, with oncogenes that encode activated Myc and Ras. These cells began to proliferate continuously ...

A review paper published last year in European Journal of Medicinal Chemistry characterized Myc as the “oncogene from ...

Just over 25 years ago, MYC, the human homologue of a retroviral oncogene, was identified. Since that time, MYC research has been intense and the advances impressive. On reflection, it is ...

Sensitivity to HAMLET is defined by oncogene expression including Ras and c-Myc and by glycolytic enzymes. Cellular targets are located in the cytoplasmic membrane, cytoskeleton, mitochondria ...