Does MYC binding to chromatin serve transcription-independent functions, including the regulation of chromosomal integrity, gene expression, chromatin structure, cellular replication and genomic ...

Researchers at Karolinska Institutet identified a super-enhancer region upstream of the MYC gene essential for tumor development and tissue repair. Cancer has often been described as a wound that ...

Researchers have long known that there is a relationship between the cancer-associated gene MYC (pronounced "Mick") and exercise adaptation. When human muscles are exercised, MYC is found to ...

The team concludes, "Taken together, these results unveil the inhibitory role of miR-377 in MYC function within PCa, thereby suggesting its potential as a therapeutic target for the treatment of ...

While Burkitt lymphoma is a rare cancer globally, its prevalence is 10 times higher in areas with a consistent presence of P. falciparum malaria ...

Various factors, including imbalances in mitochondrial protein homeostasis, elevated reactive oxygen species (ROS), discrepancies in mitochondrial and nuclear gene expression, and mitochondrial ...

Parabilis Medicines (formerly Fog Pharmaceuticals), a clinical-stage biopharmaceutical company committed to creating ...