On reflection, it is astonishing how each incremental insight into MYC regulation and function has also had an impact on numerous biological disciplines, including our understanding of molecular ...

The team concludes, "Taken together, these results unveil the inhibitory role of miR-377 in MYC function within PCa, thereby suggesting its potential as a therapeutic target for the treatment of ...

This second interaction between N-Myc and Aurora-A is particularly important ... Myc/Aurora-A interaction without inhibiting the enzyme function is therefore a significant observation," explained ...