A new study published in Life Science Alliance reveals a key genetic connection between cancer susceptibility and tissue ...

Just over 25 years ago, MYC, the human homologue of a retroviral oncogene, was identified. Since that time, MYC research has been intense and the advances impressive. On reflection, it is ...

Bailey is co-corresponding author of the team’s published paper in Nature, titled “MYC ecDNA promotes intratumor heterogeneity and plasticity in PDAC.” In their paper the researchers ...

Expression of the cell cycle inhibitor p15 INK4b is suppressed by the Myc oncoprotein and induced by transforming growth factor-β (TGF-β). The transcription factor Miz-1 activates the Ink4b ...