Broadly, these enzymes fall into 5 categories based on substrate specificity: (1) interstitial collagenases (MMP-1, -8, -13); (2) gelatinases (MMP-2,-9) and fibroblast activation protein ...

Our findings show that micromolar EGCG inhibits tumor cell invasion and directly suppresses the activity of MMP-2 and MMP-9, two of the proteases most frequently overexpressed in cancer and ...