The crystal structure of human matrix metalloproteinase type-2 (MMP-2), a key target for several anticancer therapies currently in trials, has now been solved to a 2.8Å resolution (Science 284 ...

Our data show that the EGCG concentration effective in inhibiting MMP-2 and MMP-9 is orders of magnitude ... of two gelatinases that open up pathways for cell migration. Furthermore, in addition ...