Protein domain specificity ... In this Review, we compare the major classes of MMP inhibitors and advocate that future drug discovery should be based on crucial insights into the differential ...

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MMP-2 is secreted as a proenzyme that becomes ... Researchers had previously mapped the structure of limited portions of the protein, but Karl Tryggvason and colleagues from the Karolinska ...

The study highlights the extracellular matrix protein 1 (ECM1 ... protease 1 (ADAMTS1), and matrix metalloproteinases 2 and 9 (MMP-2 and MMP-9). When ECM1 expression in hepatic stellate cells ...