The crystal structure of human matrix metalloproteinase type-2 (MMP-2), a key target for several anticancer therapies currently in trials, has now been solved to a 2.8Å resolution (Science 284 ...

The primary aim of this study was to examine resting levels of MMP-2 and -9, which are involved in the degradation of several ECM components, to assess whether sex difference exist. Additionally, we ...

MMP-13) and TIMPs (TIMP-1, TIMP-2, TIMP-3), and the housekeeping gene 18S. Data were compared using Mann Whitney U tests. Results Comparing patellar tendons from 3-year-old to 1-year-old rabbits, the ...

Our findings show that micromolar EGCG inhibits tumor cell invasion and directly suppresses the activity of MMP-2 and MMP-9, two of the proteases most frequently overexpressed in cancer and ...