MHC tetramers are typically prepared with most of the commonly used fluorescent labels used for flow cytometry. One major advantage of the technique is that the label is already attached to the ...

T cells use the T cell antigen-receptor (TCR) to recognize their antigens, which are often in the form of peptides bound to major histocompatibility complex molecules (MHC), also called HLA (human ...

In the case of neoantigens, each mass spectrometry-derived sequence that researchers use to train and test machine learning models represents a piece of an antigen and its presenting MHC molecule, ...

Recently developed major histocompatibility complex (MHC) multimer technologies allow visualization and isolation of antigen-specific T cells. However, functional analysis and in vivo transfer of ...

The major histocompatibility complex (MHC) is a cluster of genes encoding molecules that are important for lymphocyte activation. MHC molecules bind small fragments of proteins from inside a cell ...