T cells use the T cell antigen-receptor (TCR) to recognize their antigens, which are often in the form of peptides bound to major histocompatibility complex molecules (MHC), also called HLA (human ...

Detergent-solubilized MHC class II molecules (3 μM ... DO11.10 are two different lines from the same clone, using the same TCR (a gift from A. Sette, Epimmune, La Jolla, California).

Containing mutations in the MHC α3 domain that ablate CD8 binding; can be used to quantitate and to sort CD8-independent T cells. Developing high-affinity soluble antibody molecules endowed with a TCR ...

Antigen presentation by major histocompatibility complex (MHC) proteins is the caller ID of the immune system ... prediction model learned onto data from T cell receptor (TCR) response assays to ...