That difference is actually a survival benefit: The combination of two individuals' different MHC (major histocompatibility locus) genes gives their offspring an advantage in beating back disease ...

This work has extended to a new paradigm for MHC class I open conformer function ... This is a unique challenge when obtaining genetic data from highly polymorphic loci, a characteristic typical of ...

Although elegant, this model was not verified. Hybrid resistance was mapped to several putative Hh loci located close to MHC class I genes, but no corresponding genes or antigens were ever found.

Furthermore, it was assumed that identification of non-MHC diabetogenic loci in the NOD mouse would ... accurate prediction of children at high genetic risk for developing type 1 diabetes.