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Although we can provide MHC class I tetramers with either human or murine b2-microglobulin, we typically fold all tetramers of every species with human b2-microglobulin. Use of murine b2-microglobulin ...
Refer to Table 1 for the current available MHC alleles. If the requested MHC allele is not in the table or if there is other requirements, such as a specific b2-microglobulin is needed to reconstitute ...
The specificity of T cell recognition is determined by the variable (V) domain of the T cell receptor (TCR) α and β chains 1. TCR-peptide–MHC (pMHC) class I complexes for which crystal ...